The home side will enter the contest off the back of a 3-0 home defeat to Manchester City, while 12th-placed Leeds held top-four hopefuls Chelsea to a goalless draw last time out.
Earlier this season, it appeared that Fulham were destined for an immediate return to the second tier, but Scott Parker’s side have now given themselves a serious opportunity to avoid relegation.
Just two defeats from their last eight Premier League matches has helped them push towards safety, and the capital outfit are currently just two points behind 17th-placed Newcastle in the table, although the Magpies do have a game in hand on the Cottagers and will have two by the time that this game has finished.
Fulham have won three of their last seven in the league, including a famous 1-0 victory at Liverpool on March 7, but they will enter this match off the back of a 3-0 defeat at home to Man City on Saturday.
Parker’s team have now lost their last two at Craven Cottage to Tottenham Hotspur and Man City, and they will certainly be wary of what another loss could mean heading into the international break.
The fact that 16th-placed Brighton face Newcastle on Saturday makes this an even bigger game for Fulham, who suffered a 4-3 defeat when they travelled to Elland Road for the reverse clash earlier this season.
Leeds, meanwhile, will enter the match off the back of a goalless draw with Chelsea, which has to go down as a positive result for Marcelo Bielsa’s side considering the quality of the opposition.
The Whites have now won just one of their last six in the Premier League, though, losing four times in that run to Arsenal, Wolverhampton Wanderers, Aston Villa and West Ham United.
Bielsa’s team are currently 12th in the table, five points behind 10th-placed Arsenal and 10 points clear of the relegation zone, meaning that the team should still be looking up the table rather than down.
Leeds have actually lost 14 times in the Premier League this season, which is more than Fulham (13), but an impressive 11 wins from 28 matches has allowed them to be comfortably clear of the relegation zone.
The Whites have been victorious in their last two meetings with Fulham by an aggregate score of 7-3, but the Cottagers ran out 2-1 winners when the pair locked horns in London in the Championship last season.